"SkinCeuticals' A.G.E. Interrupter lowers the signs of aging caused by collagen decline," clarifies Dr. O'Connell. Being a reminder, collagen would be the protein found in pores and skin that's to blame for it's smoothness and firmness. Collagen generation decreases as we age, which is why a cream like this is vital in the regimen.9. Drink Loads of